The peptide Bremelanotide PT 141 is now used to treat sexual dysfunction in men and women. But it wasn’t originally intended for this purpose. In fact, this synthetic peptide blend was developed from Melanotan II, a hormone that can darken skin pigmentation and induce tanning.
During initial tests, the discovery that Melanotan II caused sexual arousal and erections as side effects was accidental. These effects occurred in nine out of ten male volunteers in a study conducted at the University of Arizona by Dr. Hunter Wells. Additional research found the hormone acts on the nervous system rather than regulating arousal through the vascular system like medications such as Viagra and Cialis.
How Does Bremelanotide PT 141 Work?
Bremelanotide PT 141 is a non-selective agonist or chemical that binds to and activates a cellular receptor—in this case, the melanocortin receptors associated with pigmentation. Various forms were developed after the peptide was found to be useful in treating sexual disorders. The U.S. Food and Drug Administration (FDA) halted early experiments because test subjects had experienced increases in blood pressure.
In its most current form, Bremelanotide PT 141 is administered via a subcutaneous injection. The most suitable sites for injection are where there are fat deposits. Bremelanotide is, therefore, most often injected into the stomach region, lower abdomen, or thigh. The only legitimate form of the peptide is injectable. Pills, nasal sprays, and creams with the name are not legitimate and should not be administered as such.
Effective dosages may vary as everyone responds differently to the substance. A 2-milligram dose is generally effective for men and women, about 1 hour prior to sexual activity. It’s not recommended to exceed this dosage in 72 hours, but experts suggest starting with a 1-milligram test dose and injecting a similar amount 30 minutes later; testing Bremelanotide in increments to gauge response is considered a safe approach. By consulting a physician or health care provider, you can receive a cycle protocol best suited for your condition.
In tests, some subjects responded to PT 141 in minutes. For others with sexual dysfunction, it took several hours to see the effects. The peptide’s effects can last for up to 72 hours in some people. Never Settle Labs Research was formed after we personally experienced the difficulty of sourcing high quality research materials for in-house laboratory research projects. The clear market need became apparent, innovation in this field is badly needed. That is the Story of how NSL (Never Settle Labs Research LLC) came to be. Our goal is to help propel scientific progress forward by removing barriers to innovation and increasing citizen scientist’s ability to conduct research.
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The anti-inflammatory gamma-linolenic acid in hemp may be the key constituent attributable to a proposed anti-acne action associated with this plant. Hemp may not only reduce the inflamed, swollen spots in cases of acne, but its GLA may also help to balance hormones. This would be particularly applicable to those people who notice that their acne flares in relation to their hormone levels. And don't forget, hemp has lots of proteins to help with healing, offering building blocks to help heal an acne scarred skin. You can take a two-pronged approach when using hemp in cases of acne, using it both internally and externally. You needn't worry about a hemp seed oil being too heavy or greasy for acne-prone skin because it's a readily absorbed oil, meaning that it's less likely to clog up the pores. It has also been suggested that internal use of the plant helps to prevent the hardening of sebum that blocks pores.
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